INDIGO Biosciences Blog

[Free Resource] Enzyme Induction & Its Role in Drug-Drug Interactions & Toxicity

June 18, 2019

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Through further examination of enzyme induction and its relationship to drug-drug interaction, we can better understand the effects of certain drugs and develop safer solutions for diseases and conditions.

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[Free Resource] An Overview of Nuclear Receptors & Endocrine Disruption

June 7, 2019

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From research available to us today, we know that there are many environmental chemicals that carry the potential to greatly impact the endocrine system. These are known as endocrine disrupting chemicals (EDCs), which are compounds that can alter drug and xenobiotic metabolic processes and interfere with the production, release, metabolism, and elimination of naturally occurring hormones.

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[Free Resource] A New Study on the Examination of Drug-Induced Liver Injury in upcyte® Hepatocytes

May 9, 2019

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Liver toxicity is a major cause of drug failure in clinical trials and often leads to the complete market withdrawal of many approved drugs today. Due to inherent differences in drug metabolism between species, it’s also difficult to extrapolate results obtained from preclinical animal models for human use. But new research on upcyte® hepatocytes suggests that they may be an effective solution for reducing attrition due to metabolism-mediated toxicity and the key to improving the safety of new drug candidates.

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[INFOGRAPHIC] Accelerating Scientific Decisions to Reduce Time, Cost, and Risk Associated with the Drug Discovery Process

April 16, 2019

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The drug discovery process is time-consuming, costly, and risky. Here is a quick look at some of the risks and challenges associated with drug discovery, as well as solutions that can be utilized to streamline the process to increase return-on-investment and mitigate risk.

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INDIGO Biosciences - The right partner for all your discovery and toxicology needs.

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